Caspofungin Impurity Standards

Caspofungin impurity reference standards are used by pharmaceutical quality-control laboratories, contract research organisations, and generic drug manufacturers to identify, quantify, and control Caspofungin-related impurities during analytical method development, method validation, and regulatory filing. As a echinocandin antifungal, Caspofungin requires precise characterisation of its process impurities, degradation products, and related substances to meet European Pharmacopoeia (EP), United States Pharmacopeia (USP), and British Pharmacopoeia (BP) monograph requirements. Allmpus Laboratories manufactures and supplies a comprehensive library of Caspofungin impurity standards, each provided with a Certificate of Analysis (COA) and Material Safety Data Sheet (MSDS). All products are held in-stock for rapid dispatch and are suitable for use in ANDA and DMF regulatory submissions.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

CASPOFUNGIN PNEUMOCANDIN B0 IMPURITY

Chemical Name: (3S)-(4R,5R)-N2-[(10R,12S)-10,12-Dimethy...

CAS No:
N.A.

Molecular Formula: C50H80N8O17

Molecular Weight: 1065.21

CAT No:
ALL-CAS-947

Keywords: CASPOFUNGIN PNEUMOCANDIN B0 IMPURITY

Inventory Status:1-2 WEEKS

COA MSDS

10-DEMETHYL CASPOFUNGIN

Chemical Name: (12S)-N-((2S,9R,11R,12R,14aR,15R,20R,23...

CAS No:
N.A.

Molecular Formula: C51H86N10O15

Molecular Weight: 1079.3

CAT No:
ALL-CAS-6885

Keywords: 10-DEMETHYL CASPOFUNGIN

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN

Chemical Name: (10R,12S)-N-((2R,9S,11R,12R,14aS,15S,20S...

CAS No:
c

Molecular Formula: C52H88N10O15

Molecular Weight: 1093.31

CAT No:
ALL-CAS-942

Keywords: SMILES string - O=C([C@](NC(C(NC([C@@](C...

Inventory Status:1-2 WEEKS

COA MSDS

CASPOFUNGIN ACETATE

Chemical Name: (3S,6S,9S,11R,15S,18S,20R,21S,24S,25S)-2...

CAS No:
179463-17-3

Molecular Formula: C52H88N10O15 . 2(C2H4O2)

Molecular Weight: 1213.42

CAT No:
ALL-CAS-943

Keywords: CASPOFUNGIN ACETATE

Inventory Status:1-2 WEEKS

COA MSDS

CASPOFUNGIN ACETATE AMINE IMPURITY

Chemical Name: (10R,12S)-N-((2R,9S,11R,12S,14aS,15S,20S...

CAS No:
N.A.

Molecular Formula: C50H82N8O16

Molecular Weight: 1051.2

CAT No:
ALL-CAS-7480

Keywords: CASPOFUNGIN ACETATE AMINE IMPURITY

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN ACETATE C0 ANALOG

Chemical Name: Caspofungin C0 Acetate

CAS No:
N.A.

Molecular Formula: C52H88N10O15 . 2(C2H4O2)

Molecular Weight: 1093.31

CAT No:
ALL-CAS-944

Keywords: CASPOFUNGIN ACETATE C0 ANALOG

Inventory Status:1-2 WEEKS

COA MSDS

CASPOFUNGIN DESMETHYL IMPURITY

Chemical Name: (10R,12S)-N-((2R,6S,9S,11R,12R,14aS,15S,...

CAS No:
1202167-57-4

Molecular Formula: C51H86N10O15

Molecular Weight: 1079.3

CAT No:
ALL-CAS-7574

Keywords: CASPOFUNGIN DESMETHYL IMPURITY

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN DIMER 1

Chemical Name: (4R)-N-((2S,3S,4S)-1-(((2S)-5-Amino-1-((...

CAS No:
N.A.

Molecular Formula: C102H170N18O30

Molecular Weight: 2128.6

CAT No:
ALL-CAS-2561

Keywords: CASPOFUNGIN DIMER 1

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN DIMER 2

Chemical Name: (2S,4R)-N-((2S,3S,4S)-1-(((2S)-5-Amino-1...

CAS No:
N.A.

Molecular Formula: C102H170N18O29

Molecular Weight: 2112.6

CAT No:
ALL-CAS-6951

Keywords: CASPOFUNGIN DIMER 2

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN EP IMPURITY B

Chemical Name: (10R,12S)-N-((2R,6S,9S,11R,12R,14aS,15S,...

CAS No:
N.A.

Molecular Formula: C52H88N10O15

Molecular Weight: 1093.3

CAT No:
ALL-CAS-8468

Keywords: CASPOFUNGIN EP IMPURITY B

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN EP IMPURITY C

Chemical Name: N-((2R,9S,11R,12R,14aS,16R,20S,25aS)-20-...

CAS No:
251095-73-5

Molecular Formula: C52H88N10O15

Molecular Weight: 1093.3

CAT No:
ALL-CAS-5735

Keywords: CASPOFUNGIN EP IMPURITY C

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN EP IMPURITY D

Chemical Name: (2R,4R)-N-((2S,3R)-1-((2S,4R)-2-(((2S,3S...

CAS No:
314080-31-4

Molecular Formula: C50H82N8O16

Molecular Weight: 1051.2

CAT No:
ALL-CAS-0314

Keywords: CASPOFUNGIN EP IMPURITY D

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN EP IMPURITY E

Chemical Name: (10R,12S)-N-((2R,9S,11R,12R,14aS,15S,20S...

CAS No:
150283-04-8

Molecular Formula: C50H82N8O16

Molecular Weight: 1051.2

CAT No:
ALL-CAS-3048

Keywords: CASPOFUNGIN EP IMPURITY E

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN EP IMPURITY F

Chemical Name: (2S,4R)-N-((2S,3S,4S)-1-(((2S,3R)-5-amin...

CAS No:
N.A.

Molecular Formula: C102H168N18O30

Molecular Weight: 2126.6

CAT No:
ALL-CAS-5749

Keywords: CASPOFUNGIN EP IMPURITY F

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN HYDROXYLAMINE IMPURITY

Chemical Name: (10R,12S)-N-((2R,9S,11R,12S,14aS,15S,20S...

CAS No:
1671884-42-6

Molecular Formula: C52H88N10O16

Molecular Weight: 1109.3

CAT No:
ALL-CAS-4426

Keywords: CASPOFUNGIN HYDROXYLAMINE IMPURITY

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN III

Chemical Name: 2-Ethylhexyl 2-(((2R,6S,9S,11R,12R,14aS,...

CAS No:
N.A.

Molecular Formula: C60H100N8O17S : C2H4O2

Molecular Weight: 1237.6 : 60.1

CAT No:
ALL-CAS-8492

Keywords: CASPOFUNGIN III

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN IMPURITY 1

Chemical Name: ((2R,4R)-N-((2S)-1-((2S,4R)-2-((2S,3S,4...

CAS No:
N.A.

Molecular Formula: C50H82N8O16

Molecular Weight: 1051.2

CAT No:
ALL-CAS-8947

Keywords: CASPOFUNGIN IMPURITY 1

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN IMPURITY 10

Chemical Name: (10R,12S)-N-((2R,6S,9S,11R,12S,15S,20S,2...

CAS No:
N.A.

Molecular Formula: C102H168N18O30

Molecular Weight: 2126.6

CAT No:
ALL-CAS-9521

Keywords: CASPOFUNGIN IMPURITY 10

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN IMPURITY 11

Chemical Name: (10R,12S)-N-((2R,6S,9S,11R,12S,15S,20S,2...

CAS No:
N.A.

Molecular Formula: C52H88N10O15

Molecular Weight: 1093.3

CAT No:
ALL-CAS-4825

Keywords: CASPOFUNGIN IMPURITY 11

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN IMPURITY 13

Chemical Name: (10R,12S)-N-((2R,6S,9S,11R,12S,14aS,15S...

CAS No:
1240611-93-1

Molecular Formula: C54H90N10O18

Molecular Weight: 1167.4

CAT No:
ALL-CAS-1931

Keywords: CASPOFUNGIN IMPURITY 13

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN IMPURITY 14

Chemical Name: (2S,4R)-N-((2S,3S,4S)-1-(((2S,3R)-5-Amin...

CAS No:
N.A.

Molecular Formula: C102H168N18O30

Molecular Weight: 2126.6

CAT No:
ALL-CAS-8169

Keywords: CASPOFUNGIN IMPURITY 14

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN IMPURITY 15

Chemical Name: N-((2R,6S,9S,11R,12S,14aS,20S,23S,25aS)-...

CAS No:
2142583-72-8

Molecular Formula: C52H88N10O14

Molecular Weight: 1077.3

CAT No:
ALL-CAS-3728

Keywords: CASPOFUNGIN IMPURITY 15

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN IMPURITY 16

Chemical Name: (10R,12S)-N-((2R,6S,9S,11R,12S,14aS,15S,...

CAS No:
1404083-47-1

Molecular Formula: C52H86N10O16

Molecular Weight: 1107.3

CAT No:
ALL-CAS-3471

Keywords: CASPOFUNGIN IMPURITY 16

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN IMPURITY 17

Chemical Name: (2S,4R)-N-((2S,3S,4S)-1-(((2S,3R)-5-Amin...

CAS No:
N.A.

Molecular Formula: C102H170N18O30

Molecular Weight: 2128.6

CAT No:
ALL-CAS-9572

Keywords: CASPOFUNGIN IMPURITY 17

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN IMPURITY 18

Chemical Name: (10R,12S)-N-((2R,6S,9S,11R,12S,14aS,15S...

CAS No:
2105820-54-8

Molecular Formula: C54H93N11O15

Molecular Weight: 1136.4

CAT No:
ALL-CAS-0548

Keywords: CASPOFUNGIN IMPURITY 18

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN IMPURITY 19

Chemical Name: (2R,6S,9S,11R,12S,14aS,15S,20S,23S,25aS...

CAS No:
N.A.

Molecular Formula: C52H90N10O14

Molecular Weight: 1079.3

CAT No:
ALL-CAS-8547

Keywords: CASPOFUNGIN IMPURITY 19

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN IMPURITY 2

Chemical Name: N-((2R,6S,9S,11R,14aS,15S,20S,23S,25aS)-...

CAS No:
N.A.

Molecular Formula: C51H83N7O15

Molecular Weight: 1034.3

CAT No:
ALL-CAS-7486

Keywords: CASPOFUNGIN IMPURITY 2

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN IMPURITY 20

Chemical Name: (10R,12S)-N-((2R,6S,9S,11R,14aS,15S,20S,...

CAS No:
N.A.

Molecular Formula: C50H80N8O15

Molecular Weight: 1033.2

CAT No:
ALL-CAS-7458

Keywords: CASPOFUNGIN IMPURITY 20

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN IMPURITY 21

Chemical Name: (10R,12S)-N-((2R,6S,9S,11R,12S,14aS,15S,...

CAS No:
1251833-17-6

Molecular Formula: C53H90N10O15

Molecular Weight: 1107.4

CAT No:
ALL-CAS-3176

Keywords: CASPOFUNGIN IMPURITY 21

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN IMPURITY 3

Chemical Name: N-((2R,6S,9S,14aS,15S,20S,23S,25aS)-20-(...

CAS No:
N.A.

Molecular Formula: C51H83N7O14

Molecular Weight: 1018.3

CAT No:
ALL-CAS-5962

Keywords: CASPOFUNGIN IMPURITY 3

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN IMPURITY 4

Chemical Name: (10R,12S)-N-((2R,6S,9S,11R,12S,14aS,16R,...

CAS No:
N.A.

Molecular Formula: C52H88N10O15

Molecular Weight: 1093.3

CAT No:
ALL-CAS-5963

Keywords: CASPOFUNGIN IMPURITY 4

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN IMPURITY 5

Chemical Name: (2R,4R)-N-((2S,3R)-1-((2S,4R)-2-(((2S,3S...

CAS No:
N.A.

Molecular Formula: C50H82N8O16

Molecular Weight: 1051.2

CAT No:
ALL-CAS-5964

Keywords: CASPOFUNGIN IMPURITY 5

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN IMPURITY 7

Chemical Name: (10R,12S)-N-((2R,6S,9S,11R,12S,14aS,15S,...

CAS No:
N.A.

Molecular Formula: C102H168N18O30

Molecular Weight: 2126.6

CAT No:
ALL-CAS-9527

Keywords: CASPOFUNGIN IMPURITY 7

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN IMPURITY 9

Chemical Name: (10R,12S)-N-((2R,6S,9S,11R,12S,14aS,15S,...

CAS No:
N.A.

Molecular Formula: C102H168N18O30

Molecular Weight: 2126.6

CAT No:
ALL-CAS-1847

Keywords: CASPOFUNGIN IMPURITY 9

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN ISOMER IMPURITY

Chemical Name: (10R,12S)-N-((2R,6S,9S,11R,12S,14aS,15S,...

CAS No:
N.A.

Molecular Formula: C52H88N10O15

Molecular Weight: 1093.3

CAT No:
ALL-CAS-5136

Keywords: CASPOFUNGIN ISOMER IMPURITY

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN METABOLITE-1

Chemical Name: (2R,4R)-N-((2S,3R)-1-((2S,4R)-2-(((2S,3S...

CAS No:
2758035-90-2

Molecular Formula: C50H82N8O16 : C2H4O2

Molecular Weight: 1051.2 : 60.1

CAT No:
ALL-CAS-5902

Keywords: CASPOFUNGIN METABOLITE-1

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN PHENYLTHIO AMIDE IMPURITY

Chemical Name: (3S)-(4R,5R)-N2-[(10R,12S)-10,12-Dimethy...

CAS No:
N.A.

Molecular Formula: C56H84N8O16S

Molecular Weight: 1157.38

CAT No:
ALL-CAS-945

Keywords: CASPOFUNGIN PHENYLTHIO AMIDE IMPURITY

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

CASPOFUNGIN PHENYLTHIO AMINE

Chemical Name: (3S,6S,9S,11R,15S,18S,20R,21S,24S,25S)-2...

CAS No:
N.A.

Molecular Formula: C56H86N8O15S

Molecular Weight: 1143.39

CAT No:
ALL-CAS-946

Keywords: CASPOFUNGIN PHENYLTHIO AMINE IMPURITY

Inventory Status:1-2 WEEKS

COA MSDS

CASPOFUNGIN PNEUMOCANDIN C0 IMPURITY

Chemical Name: CASPOFUNGIN PNEUMOCANDIN C0 IMPURITY

CAS No:
144074-96-4

Molecular Formula: C50H80N8O17

Molecular Weight: 1064.56

CAT No:
ALL-CAS-948

Keywords: CASPOFUNGIN PNEUMOCANDIN C0 IMPURITY

Inventory Status:1-2 WEEKS

COA MSDS

N-NITROSO CASPOFUNGIN

Chemical Name: (10R,12S)-N-((2R,9S,11R,12S,14aS,15S,20S...

CAS No:
N.A.

Molecular Formula: C52H87N11O16

Molecular Weight: 1122.3

CAT No:
ALL-CAS-8195

Keywords: N-NITROSO CASPOFUNGIN

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

PNEUMOCANDIN A0

Chemical Name: N-(20-(3-Amino-1-hydroxy-3-oxopropyl)-23...

CAS No:
120692-19-5

Molecular Formula: C51H82N8O17

Molecular Weight: 1079.3

CAT No:
ALL-CAS-2195

Keywords: PNEUMOCANDIN A0

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

PNEUMOCANDIN B0 SERINE ANALOG

Chemical Name: (10R,12S)-N-((2R,6S,9S,11R,12R,14aS,15S,...

CAS No:
258510-40-6

Molecular Formula: C49H78N8O17

Molecular Weight: 1051.2

CAT No:
ALL-CAS-0406

Keywords: PNEUMOCANDIN B0 SERINE ANALOG

Inventory Status:DELIVERY 3-4 WEEKS

COA MSDS

Key Caspofungin Impurity Variants

Caspofungin EP Impurity C (CAS 251095 — 73-5)-a specified process-related impurity listed in the Ph. Eur. monograph for caspofungin
Caspofungin EP Impurity E (CAS 150283 — 04-8)-a hydroxylated side-chain analogue recognized as a Ph. Eur. lettered impurity
Caspofungin Acetate Des — methyl Impurity-a demethylated analogue arising from incomplete side-chain methylation during synthesis
Caspofungin Acetate Isomer Impurity — a structural isomer of the parent molecule relevant to confirming chromatographic resolution and peak purity
Caspofungin Acetate Amine Impurity — a deamination- or hydrolysis-related impurity used in stability and degradation-pathway studies
Additional non — pharmacopeial impurities, including dimeric species and pneumocandin-related precursor impurities, are also available where required for impurity-origin or route-of-synthesis investigations.

Allmpus's Capability for This Drug Family

Allmpus Laboratories manufactures and supplies caspofungin and its structurally related impurities, including acetate salt forms and process-related variants relevant to the drug substance specification. Given the structural complexity of echinocandin cyclic peptides, isolating these closely related impurities requires preparative purification techniques capable of resolving compounds differing by a single functional group or stereocenter. Each compound is released with a Certificate of Analysis comprising ¹H NMR, ¹³C NMR, mass spectrometry, HPLC purity, IR, and TGA data, supporting customers' method validation, impurity qualification, and regulatory documentation requirements. Allmpus's R&D and manufacturing operations, based in Maharashtra, India, support API manufacturers, generic injectable developers, and contract research organizations sourcing caspofungin-related reference standards for QC testing and DMF/ANDA support work.

Frequently Asked Questions

Why are caspofungin impurities frequently supplied as acetate salt forms?

Caspofungin is administered clinically as caspofungin acetate, so impurity reference standards are often prepared and supplied in the same salt form to accurately match the drug substance and support direct comparison during analytical testing.

What is the difference between an EP-lettered impurity and a non-pharmacopeial impurity for caspofungin?

An EP-lettered impurity (e.g., Impurity C or E) is formally named and limited within the Ph. Eur. monograph, while a non-pharmacopeial impurity is identified during in-house method development or degradation studies but is not yet named in a compendial monograph.

Why does structural similarity make caspofungin impurity analysis challenging?

Because caspofungin is a cyclic hexapeptide with a fatty acyl side chain, many of its impurities differ by only a single hydroxyl, methyl, or amine substitution, so well-characterized reference standards are needed to confirm that HPLC methods can resolve and correctly identify each species.