Clindamycin Palmitate Impurity Standards
Clindamycin Palmitate Impurity Standards
Clindamycin Palmitate impurity reference standards are used by pharmaceutical quality-control laboratories, contract research organisations, and generic drug manufacturers to identify, quantify, and control Clindamycin Palmitate-related impurities during analytical method development, method validation, and regulatory filing. As a lincosamide antibiotic ester, Clindamycin Palmitate requires precise characterisation of its process impurities, degradation products, and related substances to meet European Pharmacopoeia (EP), United States Pharmacopeia (USP), and British Pharmacopoeia (BP) monograph requirements. Allmpus Laboratories manufactures and supplies a comprehensive library of Clindamycin Palmitate impurity standards, each provided with a Certificate of Analysis (COA) and Material Safety Data Sheet (MSDS). All products are held in-stock for rapid dispatch and are suitable for use in ANDA and DMF regulatory submissions.
7-EPI CLINDAMYCIN PALMITATE
Chemical Name: (2R,3R,4S,5R,6R)-6-((1S,2R)-2-Chloro-1-...
CAS No:
N.A
Molecular Formula: C34H63ClN2O6S
Molecular Weight: 663.4
CAT No:
ALL-C03263
Keywords: SMILES string - CN1[C@H](C(N[C@@H]([C@@H...
Inventory Status:IN STOCK/11-282
ANISYLIDENE CLINDAMYCIN IMPURITY
Chemical Name: (2S,4R)-N-((1S,2S)-2-Chloro-1-((2R,3aS,4...
CAS No:
N.A
Molecular Formula: C26H39ClN2O6S
Molecular Weight: 543.1
CAT No:
ALL-CLI-AC
Keywords: SMILES string - [H][C@@]12[C@](O)([H])[...
Inventory Status:IN STOCK/11-283
CLINDAMYCIN PENTADECANOATE IMPURITY
Chemical Name: Methyl 7-Chloro-6,7,8-trideoxy-6-[[[(2S,...
CAS No:
1123211-67-5
Molecular Formula: C33H61ClN2O6S
Molecular Weight: 649.37
CAT No:
ALL-C03238
Keywords: SMILES string - C[C@H](Cl)[C@@]([C@@]([C...
Inventory Status:IN STOCK
CLINDAMYCIN 2, 3 DIPALMIATE
Chemical Name: (Methyl 7-chloro-6,7,8-trideoxy-6-(1-met...
CAS No:
N.A
Molecular Formula: C50H93ClN2O7S
Molecular Weight: 901.80 g/mol
CAT No:
ALL-C04464
Keywords: Clindamycin 2, 3 Dipalmiate
Inventory Status:Delivery 3-4 weeks (Custom Synthesis)
CLINDAMYCIN 2,4-DIPALMITATE
Chemical Name: (2R,3R,4S,5R,6R)-2-((1S,2S)-2-Chloro-1-...
CAS No:
N.A
Molecular Formula: C50H93ClN2O7S
Molecular Weight: 901.8
CAT No:
ALL-C08152
Keywords: SMILES string - CS[C@@H]1[C@H](OC(CCCCCC...
Inventory Status:Delivery 3-4 weeks (Custom Synthesis)
CLINDAMYCIN 3-PALMITATE
Chemical Name: 2-(2-Chloro-1-(1-methyl-4-propylpyrrolid...
CAS No:
68225-59-2 (HCl)
Molecular Formula: C34H63ClN2O6S
Molecular Weight: 663.4
CAT No:
ALL-C04449
Keywords: SMILES string - CC1CCC(OC1(C(=O)C(=O)N2C...
Inventory Status:IN STOCK
CLINDAMYCIN B-PALMITATE
Chemical Name: 6-(2-Chloro-1-(4-ethyl-1-methylpyrrolidi...
CAS No:
68206-99-5
Molecular Formula: C33H61ClN2O6S
Molecular Weight: 649.37
CAT No:
ALL-C03265
Keywords: Clindamycin B-Palmitate/68206-99-5
Inventory Status:IN STOCK/11-270
CLINDAMYCIN HEPTADECANOATE IMPURITY
Chemical Name: Methyl 7-Chloro-6,7,8-trideoxy-6-[[[(2S,...
CAS No:
1123211-69-7
Molecular Formula: C35H65ClN2O6S
Molecular Weight: 677.4
CAT No:
ALL-C03210
Keywords: SMILES string - O=C(OC1C(OC(C(O)C1O)C(NC...
Inventory Status:IN STOCK/11-268
CLINDAMYCIN LAURATE HCL
Chemical Name: (2R,3R,4S,5R,6R)-6((1S,2S)-2-chloro-1-((...
CAS No:
25507-13-5
Molecular Formula: C30H55ClN2O6S.HCl
Molecular Weight: 643.76 g/mol
CAT No:
ALL-C07436
Keywords: SMILES string - C[C@H](Cl)[C@@]([C@@]([C...
Inventory Status:DELIVERY IMMEDIATE
CLINDAMYCIN MYRISTATE
Chemical Name: Methyl 7-Chloro-6,7,8-trideoxy-6-[[[(2S...
CAS No:
1123211-66-4
Molecular Formula: C32H59ClN2O6S
Molecular Weight: 635.4
CAT No:
ALL-C03211
Keywords: SMILES string - C[C@H](Cl)[C@@]([C@@]([C...
Inventory Status:IN STOCK/11-278
CLINDAMYCIN PALMITATE
Chemical Name: (2R,3R,4S,5R,6R)-6-((1S,2S)-2-Chloro-1-(...
CAS No:
36688-78-5 (FREE BASE)
Molecular Formula: C34H63ClN2O6S (FREE BASE)
Molecular Weight: 663.39 (FREE BASE)
CAT No:
ALL-C03229
Keywords: SMILES string - CS[C@@H]1[C@H](OC(CCCCCC...
Inventory Status:IN STOCK/11-275
CLINDAMYCIN PALMITATE SULFOXIDE (ALPHA,BETA ISOMER)
Chemical Name: Methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,...
CAS No:
2126928-92-3/1123211-65-3 (Free Base)
Molecular Formula: C34H63ClN2O7S (FREE BASE)
Molecular Weight: 679.39 (FREE BASE)
CAT No:
ALL-C03229
Keywords: SMILES string - O=C([C@@H]1C[C@H](CN1C)C...
Inventory Status:IN STOCK/11-281
CLINDAMYCIN STEARATE
Chemical Name: Methyl 7-Chloro-6,7,8-trideoxy-6-[[[(2S,...
CAS No:
1123211-70-0
Molecular Formula: C36H67ClN2O6S
Molecular Weight: 691.5
CAT No:
ALL-C03209
Keywords: SMILES string - C[C@H](Cl)[C@@]([C@@]([C...
Inventory Status:IN STOCK/11-267
CLINDAMYCIN-4-PALMITATE
Chemical Name: (2R,3R,4R,5R,6R)-2-((1S,2S)-2-Chloro-1-...
CAS No:
25507-04-4
Molecular Formula: C34H63ClN2O6S . HCl
Molecular Weight: 699.85
CAT No:
ALL-C04450
Keywords: SMILES string - CC1CCC(OC1(C(=O)C(=O)N2C...
Inventory Status:IN STOCK/11-273
Key Clindamycin Palmitate Impurity Variants
- Clindamycin Palmitate Sulfoxide (alpha/beta isomers) — oxidation products at the sulfur center, identified as a major impurity class in published characterization studies
- Clindamycin B — Palmitate (CAS 68206-99-5)-a palmitate ester of the clindamycin B structural variant, relevant to confirming impurity origin from starting material
- Clindamycin Stearate (CAS 1123211 — 70-0)-a longer-chain fatty acid ester analogue formed from incomplete selectivity during esterification
- Epiclindamycin Palmitate — the palmitate ester of 7-epiclindamycin, combining stereochemical epimerization with esterification-related impurity formation
- Clindamycin 2,4 — Dipalmitate-a diester impurity arising from esterification at an additional hydroxyl position
- Additional chain — length variants (myristate, laurate, pentadecanoate, heptadecanoate) and the 3-isomer positional variant are available where full impurity-profile coverage is required.
Allmpus's Capability for This Drug Family
Allmpus Laboratories manufactures and supplies clindamycin palmitate and its related structural impurities as part of a broader clindamycin-family portfolio that also spans clindamycin hydrochloride and clindamycin phosphate impurities. Because clindamycin palmitate impurities frequently differ from the parent compound only in fatty-acid chain length, ester position, or sulfur oxidation state, isolating and confirming these closely related species requires preparative purification techniques capable of resolving subtle structural differences. Each compound is released with a Certificate of Analysis comprising ¹H NMR, ¹³C NMR, mass spectrometry, HPLC purity, IR, and TGA data, supporting customers' method validation, impurity qualification, and regulatory documentation requirements. Allmpus's R&D and manufacturing operations, based in Maharashtra, India, support API manufacturers, generic drug developers, and contract research organizations sourcing clindamycin-related reference standards for QC testing and DMF/ANDA support work.
Frequently Asked Questions
Why doesn't clindamycin palmitate have Ph. Eur. lettered impurities the way clindamycin hydrochloride does?
Clindamycin palmitate impurities are primarily tracked under the USP Pharmaceutical Analytical Impurity (PAI) system using descriptive names or impurity numbers, rather than under a Ph. Eur. lettered scheme specific to the palmitate ester, reflecting how this particular drug substance's related substances have been characterized and cataloged.
Why do fatty-acid chain-length variants (stearate, myristate, laurate) appear as impurities in clindamycin palmitate?
These arise from incomplete selectivity during the esterification reaction with palmitic acid, where fatty acids of slightly different chain length can react with clindamycin's hydroxyl group, producing structurally similar ester impurities that must be resolved and quantified.
What documentation is provided with clindamycin palmitate impurity standards?
Each standard is supplied with a Certificate of Analysis including spectroscopic (NMR, MS, IR) and chromatographic (HPLC) data, along with thermal analysis (TGA) where applicable, to support characterization and regulatory documentation requirements.