Cyanocobalamin Impurity Standards

Cyanocobalamin impurity reference standards are used by pharmaceutical quality-control laboratories, contract research organisations, and generic drug manufacturers to identify, quantify, and control Cyanocobalamin-related impurities during analytical method development, method validation, and regulatory filing. As a vitamin B12 compound, Cyanocobalamin requires precise characterisation of its process impurities, degradation products, and related substances to meet European Pharmacopoeia (EP), United States Pharmacopeia (USP), and British Pharmacopoeia (BP) monograph requirements. Allmpus Laboratories manufactures and supplies a comprehensive library of Cyanocobalamin impurity standards, each provided with a Certificate of Analysis (COA) and Material Safety Data Sheet (MSDS). All products are held in-stock for rapid dispatch and are suitable for use in ANDA and DMF regulatory submissions.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

8-EPI- CYANOCOBALAMIN (IMP E) / CYANOCOBALAMIN EP IMPURITY E

Chemical Name: (8R)-Coα-[α-(5,6-dimethylbenzimidazoly...

CAS No:
41325-63-7

Molecular Formula: C63H88CoN14O14P

Molecular Weight: 1355.4

CAT No:
ALL-C07094

Keywords: SMILES string -N#[C-][Co+3]123([N]4=CN([...

Inventory Status:IN STOCK/89-1608

COA MSDS

CYANOCOBALAMIN 13C7

Chemical Name: Cyanocobalamin 13C7

CAS No:
N.A.

Molecular Formula: C5613C7H88CoN14O14P

Molecular Weight: 1362.3

CAT No:
ALL-C04073

Keywords: SMILES string - N#[C-][Co+3]123([N]4=[13...

Inventory Status:IN STOCK/89-1618

COA MSDS

CYANOCOBALAMIN B5-HYDROXYMETHYL DERIVATIVE

Chemical Name: Cyanocobalamin B5-Hydroxymethyl Derivati...

CAS No:
N.A.

Molecular Formula: C64H90CoN14O14P

Molecular Weight: 1369.4

CAT No:
ALL-C04072

Keywords: SMILES string - N#[C-][Co+3]123([N]4=CN(...

Inventory Status:IN STOCK/89-1617

COA MSDS

CYANOCOBALAMIN B6-HYDROXYMETHYL DERIVATIVE

Chemical Name: Cyanocobalamin B6-Hydroxymethyl Derivati...

CAS No:
N.A

Molecular Formula: C64H90CoN14O14P

Molecular Weight: 1369.4

CAT No:
ALL-C04071

Keywords: SMILES string - N#[C-][Co+3]123([N]4=CN(...

Inventory Status:IN STOCK/89-1616

COA MSDS

CYANOCOBALAMIN EP IMPURITY A

Chemical Name: Coα-[α-(5,6-dimethylbenzimidazolyl)]-C...

CAS No:
23208-66-4

Molecular Formula: C63H85CoN13O15P

Molecular Weight: 1354.4

CAT No:
ALL-C05166

Keywords: SMILES string - N#[C-][Co+3]1([N-]2[C@@]...

Inventory Status:IN STOCK/89-1606

COA MSDS

CYANOCOBALAMIN EP IMPURITY B

Chemical Name: Coα-[α-(5,6-dimethylbenzimidazolyl)]-C...

CAS No:
26264-28-8

Molecular Formula: C63H87CoN13O15P

Molecular Weight: 1356.4

CAT No:
ALL-C05232

Keywords: SMILES string - N#[C-][Co+3]123([N]4=CN(...

Inventory Status:IN STOCK/89-1610

COA MSDS

CYANOCOBALAMIN EP IMPURITY G

Chemical Name: Coα-[α-(5,6-dimethylbenzimidazolyl)]-C...

CAS No:
N.A

Molecular Formula: C64H90CoN14O14P

Molecular Weight: 1369.4

CAT No:
ALL-C07121

Keywords: SMILES string - N#[C-][Co+3]123([N]4=CN(...

Inventory Status:IN STOCK/89-1611

COA MSDS

CYANOCOBALAMIN EP IMPURITY H

Chemical Name: Coα-[α-(5,6-dimethylbenzimidazolyl)]-C...

CAS No:
13422-51-0

Molecular Formula: C64H90CoN14O14P

Molecular Weight: 1369.4

CAT No:
ALL-C04067

Keywords: SMILES string -C[C@@]12[N]([Co+3]34([N]5...

Inventory Status:IN STOCK/89-1612

COA MSDS

CYANOCOBALAMIN IMPURITY 1

Chemical Name: Cyanocobalamin Impurity 1

CAS No:
N.A

Molecular Formula: C66H92CoN14O16P

Molecular Weight: 1427.5

CAT No:
ALL-C04056

Keywords: SMILES string - N#[C-][Co+3]123([N]4=CN(...

Inventory Status:IN STOCK/89-1601

COA MSDS

CYANOCOBALAMIN IMPURITY 2

Chemical Name: Cyanocobalamin Impurity 2

CAS No:
N.A

Molecular Formula: C63H86CoN14O14P

Molecular Weight: 1353.4

CAT No:
ALL-C04057

Keywords: SMILES string - N#[C-][Co+3]123([N]4=CN(...

Inventory Status:IN STOCK/89-1602

COA MSDS

CYANOCOBALAMIN IMPURITY 3

Chemical Name: Cyanocobalamin Impurity 3

CAS No:
N.A.

Molecular Formula: C63H88Co3N14O15P

Molecular Weight: 1489.3

CAT No:
ALL-C04058

Keywords: SMILES string - C[C@@]12[N]([Co+3]34([N]...

Inventory Status:IN STOCK/89-1603

COA MSDS

CYANOCOBALAMIN IMPURITY 4

Chemical Name: Cyanocobalamin Impurity 4

CAS No:
N.A.

Molecular Formula: C62H89CoN14O14P

Molecular Weight: 1344.4

CAT No:
ALL-C04060

Keywords: SMILES string - N#[C-][Co+3]123([N]4=CN(...

Inventory Status:IN STOCK/89-1605

COA MSDS

CYANOCOBALAMIN IMPURITY 5

Chemical Name: Cyanocobalamin Impurity 5

CAS No:
121483-62-3

Molecular Formula: C63H87CoN13O15P

Molecular Weight: 1356.4

CAT No:
ALL-C04070

Keywords: SMILES string - N#[C-][Co+3]123([N]4=CN(...

Inventory Status:IN STOCK/89-1615

COA MSDS

CYANOCOBALAMIN IMPURITY C

Chemical Name: Coα-[α-(5,6-dimethylbenzimidazolyl)]-C...

CAS No:
38218-51-8

Molecular Formula: C64H90CoN14O14P

Molecular Weight: 1369.4

CAT No:
ALL-C05617

Keywords: SMILES string - N#[C-][Co+3]123([N]4=CN(...

Inventory Status:IN STOCK/89-1607

COA MSDS

CYANOCOBALAMIN IMPURITY D/32-CARBOXYCYANOCOBALAMIN

Chemical Name: Coα-[α-(5,6-dimethylbenzimidazolyl)]-C...

CAS No:
N.A

Molecular Formula: C63H87CoN13O15P

Molecular Weight: 1356.4

CAT No:
ALL-C07093

Keywords: SMILES string - N#[C-][Co+3]123([N]4=CN(...

Inventory Status:IN STOCK/89-1609

COA MSDS

CYANOCOBALAMIN OXIDATION IMPURITY

Chemical Name: Cyanocobalamin Oxidation Impurity

CAS No:
N.A

Molecular Formula: C63H88CoN14O15P

Molecular Weight: 1371.4

CAT No:
ALL-C04069

Keywords: SMILES string -NC(CC[C@H]1[C@@](CC(N)=O)...

Inventory Status:IN STOCK/89-1614

COA MSDS

CYANOCOBALAMIN | VITAMIN B12

Chemical Name: 5,6-Dimethyl-1-(3-O-phosphono-α-D-ribof...

CAS No:
68-19-9

Molecular Formula: C63H88CoN14O14P

Molecular Weight: 1355.4

CAT No:
ALL-C04055

Keywords: SMILES string - N#[C-][Co+3]123([N]4=CN(...

Inventory Status:IN STOCK/89-1600

COA MSDS

METHYLCOBALAMIN

Chemical Name: Methyl-5,6-dimethylbenzimidazolylcobalam...

CAS No:
13422-55-4

Molecular Formula: C63H91CoN13O14P

Molecular Weight: 1344.4

CAT No:
ALL-C04068

Keywords: SMILES string - C[C@@]12[N]([Co+3]34([N]...

Inventory Status:IN STOCK/89-1613

COA MSDS

VITAMIN B-12 C-LACTAM

Chemical Name: Cobinic acid-abdeg-pentamide, 8-amino-, ...

CAS No:
23388-02-5

Molecular Formula: C63H86CoN14O14P

Molecular Weight: 1353.4

CAT No:
ALL-C04059

Keywords: SMILES string - N#[C-][Co+3]1([N-]2[C@@]...

Inventory Status:IN STOCK/89-1604

COA MSDS

Key Cyanocobalamin Impurity Variants Available

Cyanocobalamin EP Impurity A (7β,8β — Lactocyanocobalamin / Vitamin B12 c-Lactone)-a lactonized degradation-related corrinoid impurity
Cyanocobalamin EP Impurity B (50 — Carboxycyanocobalamin / Vitamin B12 e-Monocarboxylic Acid)-a carboxylic acid hydrolysis product of the corrin ring amide side chains
Cyanocobalamin EP Impurity C (Nb — Methylcyanocobalamin / 34-Methylcyanocobalamin)-an N-methylated benzimidazole nucleotide impurity
Cyanocobalamin EP Impurity H (Hydroxocobalamin — related)-an impurity linked to the hydroxocobalamin/aquacobalamin equilibrium form of the corrinoid
Pseudo — Vitamin B12-a naturally co-produced corrinoid analog lacking the correct lower nucleotide, commonly monitored as a related substance in fermentation-derived Cyanocobalamin

Allmpus Capability for the Cyanocobalamin/Corrinoid Family

Allmpus Laboratories manufactures and isolates Cyanocobalamin impurities using preparative isolation techniques suited to the complex, cobalt-centered corrin structure and the close chromatographic behavior of related corrinoid congeners. Each impurity is supplied with a Certificate of Analysis supported by ¹H NMR, ¹³C NMR, mass spectrometry, HPLC, IR, and TGA data, allowing customers to confirm structural identity and purity before use in stability-indicating method development, method validation, or routine quality control testing of Cyanocobalamin drug substance and injectable, oral, and nutraceutical dosage forms. Allmpus's capability in this space is built for the resolution demands specific to corrinoid analogs, and impurities are manufactured at its Dombivali, Maharashtra facility for supply to pharmaceutical manufacturers and contract testing laboratories.

Frequently Asked Questions

Are Allmpus Cyanocobalamin impurity standards referenced to EP and USP designations?

Yes. Where a pharmacopeial designation exists, the corresponding EP impurity letter is provided along with the chemical name and any commonly used synonym, to support direct use in monograph-based testing.

What analytical data is provided with each impurity standard?

Each standard is issued with a Certificate of Analysis that includes NMR (¹H and ¹³C), mass spectrometry, HPLC purity, IR, and TGA data to support identity and purity confirmation.

Are these standards suitable for human use?

No. Cyanocobalamin impurity standards are supplied strictly for analytical, research, and reference purposes, including method development and quality control testing, and are not intended for human or veterinary administration.