Rifampicin Impurity Standards
Rifampicin Impurity Standards
Rifampicin impurity reference standards are used by pharmaceutical quality-control laboratories, contract research organisations, and generic drug manufacturers to identify, quantify, and control Rifampicin-related impurities during analytical method development, method validation, and regulatory filing. As a rifamycin antibiotic, Rifampicin requires precise characterisation of its process impurities, degradation products, and related substances to meet European Pharmacopoeia (EP), United States Pharmacopeia (USP), and British Pharmacopoeia (BP) monograph requirements. Allmpus Laboratories manufactures and supplies a comprehensive library of Rifampicin impurity standards, each provided with a Certificate of Analysis (COA) and Material Safety Data Sheet (MSDS). All products are held in-stock for rapid dispatch and are suitable for use in ANDA and DMF regulatory submissions.
25-DEACETOXY-25-HYDROXYRIFAMYCIN S
Chemical Name: (9E,19E,21E)-2,13,15,17-Tetrahydroxy-11-...
CAS No:
17555-51-0
Molecular Formula: C35H43NO11
Molecular Weight: 653.73
CAT No:
ALL-R03981
Keywords: SMILES string - O=C1C2=C(C(C=C3NC(/C(C)=...
Inventory Status:IN STOCK
25-DEACETYL-23-ACETYL RIFAMPICIN
Chemical Name: 25-Deacetyl 23-Acetyl Rifampicin
CAS No:
1416773-23-3
Molecular Formula: C43H58N4O12
Molecular Weight: 822.94
CAT No:
ALL-RIF-1961
Keywords: SMILES string -OC(C(/C=N/N(CC1)CCN1C)=C2...
Inventory Status:UNDER DEVOLPMENT
3-FORMYL RIFAMYCIN
Chemical Name: 1,2-Dihydro-5,6,9,17,19,21-hexahydroxy-2...
CAS No:
13292-22-3
Molecular Formula: C₃₈H₄₇NO₁₃
Molecular Weight: 725.78
CAT No:
ALL-RIF-1969
Keywords: SMILES string - OC1=C(C(O)=C(NC(/C(C)=C\...
Inventory Status:IN STOCK
RIFAMPICIN
Chemical Name: 25-O-Deacetyl-3-[(E)-[(4-methyl-1-pipera...
CAS No:
13292-46-1
Molecular Formula: C41H56N4O11
Molecular Weight: 780.9
CAT No:
ALL-RIF-1962
Keywords: Rifampicin Impurity
Inventory Status:IN STOCK
RIFAMPICIN 21-O-ACETYL ANALOUGE
Chemical Name: 25-Deacetyl 21-Acetyl Rifampicin
CAS No:
1416773-22-2
Molecular Formula: C43H58N4O12
Molecular Weight: 822.94
CAT No:
ALL-RIF-1963
Keywords: SMILES string - OC(C(C=NN(CC1)CCN1C)=C2...
Inventory Status:UNDER DEVELOPMENT
RIFAMPICIN 25-DESACETYL IMPURITY
Chemical Name: 25-O-Deacetyl-3-[(E)-[(4-methyl-1-pipera...
CAS No:
16783-99-6
Molecular Formula: C41H56N4O11
Molecular Weight: 780.9
CAT No:
OLYRIF0010.0DA
Keywords: SMILES string - OC(C(/C=N/N1CCN(C)CC1)=C...
Inventory Status:IN STOCK-401-70
RIFAMPICIN DESACETYL QUINONE IMPURITY
Chemical Name: 25-Deacetyl-1,4-didehydro-1,4-dideoxy-3-...
CAS No:
65110-92-1
Molecular Formula: C41H54N4O11
Molecular Weight: 778.89
CAT No:
ALL-RIF-1965
Keywords: PHARMACEUTICAL IMPURITIES LIKE RIFAMPICI...
Inventory Status:IN STOCK-402-70
RIFAMPICIN EP IMPURITY A | RIFAMPICIN QUINONE
Chemical Name: 1,4-Dideoxy-1,4-dihydro-3-[(E)-[(4-methy...
CAS No:
13983-13-6
Molecular Formula: C43H56N4O12
Molecular Weight: 820.92
CAT No:
ALL-R03432
Keywords: SMILES string - CN1CCN(/N=C/C2=C(NC(/C(...
Inventory Status:IN STOCK-403-70
RIFAMPICIN EP IMPURITYB | RIFAMPICIN N-OXIDE IMPURITY
Chemical Name: 3-[[(4-Methyl-4-oxido-1-piperazinyl)imin...
CAS No:
125833-03-6
Molecular Formula: C43H58N4O13
Molecular Weight: 838.94
CAT No:
ALL-RIF-1967
Keywords: SMILES string - OC1=C(C(NC(/C(C)=C\C=C\...
Inventory Status:IN STOCK-404-70
RIFAMPICIN N-DESMETHYL IMPURITY
Chemical Name: 3-[(1-Piperazinylimino)methyl]-rifamycin
CAS No:
13292-45-0
Molecular Formula: C42H56N4O12
Molecular Weight: 808.91
CAT No:
ALL-RIF-1968
Keywords: PHARMACEUTICAL IMPURITIES LIKE RIFAMPICI...
Inventory Status:IN STOCK-405-70
RIFAMPICIN N-OXIDE | RIFAXIMIN IMINE-N-OXIDE
Chemical Name: 1-[(7S,9E,11S,12R,13S,14R,15R,16R,17S,18...
CAS No:
51963-55-4
Molecular Formula: C43H58N4O13
Molecular Weight: 838.9
CAT No:
ALL-R03264
Keywords: SMILES string - O=C1C2=C(O[C@]1(C)O/C=C...
Inventory Status:IN STOCK
Key Rifampicin impurity variants available
- Rifampicin EP Impurity A (Rifampicin Quinone) — CAS 13983-13-6
- Rifampicin EP Impurity B (Rifampicin N — Oxide)-CAS 125833-03-6
- 3 — Formyl Rifamycin-CAS 13292-22-3
- 3 — Formyl Rifamycin Isonicotinoyl Hydrazone-CAS 13292-53-0
- Rifampicin — d3 (deuterium-labeled internal standard)-CAS 1262052-36-7
Allmpus Capability for This Drug Family
Allmpus Laboratories Private Limited, based in India, works across the design, research, and cost-effective synthesis of API-related compounds, process impurities, and metabolites, including those in the rifamycin/rifampicin family. Our approach combines custom synthesis routes with isolation and purification techniques developed to deliver well-characterized impurity standards suitable for method development, method validation, and genotoxic impurity assessment. Each standard is supplied with supporting analytical data intended to meet the documentation expectations of regulatory agencies, helping clients progress ANDA and DMF filings without gaps in impurity characterization.
Frequently Asked Questions
1. Why are impurities like Rifampicin N-Oxide and Rifampicin Quinone significant in QC testing?
These are recognized degradation products formed under oxidative or hydrolytic conditions. Compendial methods require their identification and quantification within specified limits to confirm that a rifampicin batch meets EP or USP purity criteria and remains stable over its shelf life.
2. Can Allmpus supply deuterium-labeled Rifampicin standards for mass spectrometry work?
Yes. Isotopically labeled variants, such as Rifampicin-d3, are available and are commonly used as internal standards in LC-MS/MS quantification workflows where isotope dilution improves measurement accuracy.
3. Are Rifampicin impurity standards from Allmpus intended for clinical or human use?
No. These reference standards are intended solely for analytical and research applications, including method development, validation, and quality control testing, and are not intended for human or veterinary administration.